Ischaemia and hypoxia: the therapeutic options

Abstract

Complex wounds are often associated with inadequate perfusion with resulting decreased oxygenation. Failure to diagnose ischaemia or hypoxia could lead to complications, including loss of limb and even life. In all cases patient management should focus on restoring the arterial circulation, i.e. perfusion strategies. In selected cases this might not be possible and adjuvant modalities should be utilised to improve oxygen delivery (oxygenation strategies). This article will provide the background information to guide the clinician through the decision-making process.